US Highway 72 which runs from East-West from Chattanooga to Memphis passes through Florence. Most major attractions, hotels,restaurants, etc are located on or near US 72 or Florence Blvd as its known within the City of Florence. US Highway 43 runs North-South from Nashville, TN to Mobile Alabama. It travels the same path as US 72 through Florence.
Florence lies about 48 miles west of Interstate 65 Exit 351 in Athens, Exits 340A-340B Decatur/Huntsville, Exit 310 at Cullman.
Near Florence, there are a few options for flying in and out. Delta Air Lines has service to Northwest Alabama Regional Airport. More flights can be found leaving from Huntsville, AL; Birmingham, AL; Nashville,TN; and Memphis, TN. Huntsville would be the shortest drive at just over one hour. The others are a little more than two hours drive.
- 1 Northwest Alabama Regional Airport (MSL IATA), 1729 T. Ed Campbell Drive, Suite A in Muscle Shoals, AL, ☎+1 256 381-2869, fax: +1 256 381-2915, e-mail: firstname.lastname@example.org.
- Port of Huntsville (HSV IATA), 1000 Glenn Hearn Blvd, Huntsville, AL, ☎+1 256 772-9395, fax: +1 256 772-0305, e-mail: email@example.com.