Therese Huber (7 May 1764 – 15 June 1829) was a German author. She was one of the so-called Universitätsmamsellen [de; es; fr], a group of five academically active women during the mid-18th and early 19th centuries. The group consisted of daughters of academics at Göttingen University; Huber was noteworthy among them, alongside Meta Forkel-Liebeskind, Caroline Schelling, Philippine Engelhard, and Dorothea Schlözer.
Therese Huber was born Marie Therese Heyne in Göttingen as daughter of the influential classical philologist Christian Gottlob Heyne and his first wife Therese (1730-1775), the daughter of lutenist and composer Sylvius Leopold Weiss. She married traveller and ethnologist Georg Forster in 1785. They lived in Wilno 1785–1787 and in Göttingen and Mainz 1788–1792 and had three children, but an unhappy marriage. After Forster had left Mainz for Paris as representative of the Mainz Republic, she and her lover Ludwig Ferdinand Huber, who had been living with the Forsters in Mainz, moved to Neuchâtel, living under difficult conditions there. She and Forster met for the last time in 1793, when he agreed to a divorce. However, Forster died soon after, and she married her lover. After his 1804 death, she moved in with her daughter in Ulm. Huber died in 1829 in Augsburg. The most notable of her ten children, four of which survived to adulthood, was social reformer Victor Aimé Huber. She had a long and regular correspondence with her unmarried daughter Therese Forster, who edited Georg Forster’s complete works in 1843.